GH secretagogue research
Ipamorelin.
3 vendors · $17–22
Synthetic pentapeptide described in 1998 by Novo Nordisk researchers as a selective ghrelin/GH-secretagogue receptor agonist; researched for growth-hormone release. Not approved for human therapeutic use.
SequenceAib-His-D-2-Nal-D-Phe-Lys-NH₂
Compound specification
Formula
C₃₈H₄₉N₉O₅
CAS
170851-70-4
MW
711.9 g/mol
Half-life
2 hours (terminal half-life, human IV-infusion study; Gobburu et al. 1999)
Storage
Lyophilised powder below −15 °C in a tightly closed container, shielded from light; equilibrate the sealed vial to room temperature before opening. Reconstituted vials 2–8 °C.
Sizes
2 mg, 5 mg, 10 mg
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Representative literature
Research context. Recent peer-reviewed work.
1998 · Eur. J. Endocrinol.
Ipamorelin, the first selective growth hormone secretagogue
1999 · Pharm. Res.
Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers
2014 · Int. J. Colorectal Dis.
Prospective, randomized, controlled, proof-of-concept study of the ghrelin mimetic ipamorelin for the management of postoperative ileus
cited by n = 117
Long-form research guide
Weight Loss Research. Mechanism + protocols + safety.
Lipolysis, GH secretagogues, and adipose tissue modulation in obesity models
Open the long-form guide for Ipamorelin →